{"id":6415,"date":"2025-05-01T22:50:21","date_gmt":"2025-05-01T22:50:21","guid":{"rendered":"https:\/\/adjuvants.com\/?post_type=product&#038;p=6415"},"modified":"2026-07-09T21:46:14","modified_gmt":"2026-07-09T21:46:14","slug":"lit4-2","status":"publish","type":"product","link":"https:\/\/adjuvants.com\/?product=lit4-2","title":{"rendered":"LiT4\u2122"},"content":{"rendered":"\t\t<div data-elementor-type=\"product-post\" data-elementor-id=\"6415\" class=\"elementor elementor-6415\" data-elementor-post-type=\"product\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4ba1626e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4ba1626e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5f56e8fc\" data-id=\"5f56e8fc\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-71c3761a elementor-widget elementor-widget-text-editor\" data-id=\"71c3761a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tLiT4\u2122 is a TLR4 agonist in a liposomal formulation of about 100 nm in average diameter. The TLR4 agonist produces a potent, balanced immune response with a T&lt;sub&gt;H&lt;\/sub&gt;1 bias. Each 0.5 mL vial contains 5o \u00b5g TLR agonist.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2247553 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2247553\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-770b089\" data-id=\"770b089\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c31a45f elementor-widget elementor-widget-woocommerce-product-short-description\" data-id=\"c31a45f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"woocommerce-product-short-description.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"woocommerce-product-details__short-description\">\n\t<h4>LiT4\u2122<br \/>\nTLR4 in a Liposome<\/h4>\n<p>Liposomes consist of vesicles formed by the assembly of phospholipid bilayers. \u00a0These vesicles can be made at ~100 nm diameters and have good stability. \u00a0Liposomes are versatile and biocompatible vehicles for adjuvant formulation. \u00a0As an amphiphilic molecule, the TLR4 agonist will be localized within the lipid bilayer. Furthermore, aqueous adjuvants such as QS21 can be encapsulated in the aqueous interior of the liposomes or solubilized in the aqueous bulk phase forming an adjuvant like the established adjuvant AS01B which has demonstrated good results in malaria, shingles, and TB.<\/p>\n<hr \/>\n<p><strong>Sold in a vial of 0.5 mL.<br \/>\n<\/strong>Research-grade only. Inquire about cGMP.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e74fbcd elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e74fbcd\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3bcb319\" data-id=\"3bcb319\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-06f771b elementor-grid-4 elementor-grid-tablet-3 elementor-grid-mobile-2 elementor-products-grid elementor-wc-products show-heading-yes elementor-widget elementor-widget-woocommerce-product-related\" data-id=\"06f771b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"woocommerce-product-related.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t<section class=\"related products\">\n\n\t\t\t\t\t<h2>Related products<\/h2>\n\t\t\t\t<ul class=\"products elementor-grid columns-4\">\n\n\t\t\t\n\t\t\t\t\t<li class=\"desktop-align-left tablet-align-left mobile-align-left product type-product post-6032 status-publish first instock product_cat-tlr4-agonists has-post-thumbnail taxable shipping-taxable purchasable product-type-simple\">\n\t<a href=\"https:\/\/adjuvants.com\/?product=mit4\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><img fetchpriority=\"high\" decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_MIT4_1200x-768x768.jpg\" class=\"attachment-woocommerce_thumbnail size-woocommerce_thumbnail\" alt=\"MiT4\u2122\" srcset=\"https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_MIT4_1200x-768x768.jpg 768w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_MIT4_1200x-300x300.jpg 300w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_MIT4_1200x-1024x1024.jpg 1024w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_MIT4_1200x-150x150.jpg 150w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_MIT4_1200x-200x200.jpg 200w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_MIT4_1200x-100x100.jpg 100w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_MIT4_1200x.jpg 1200w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><h2 class=\"woocommerce-loop-product__title\">MiT4\u2122<\/h2>\n\t<span class=\"price\"><span class=\"woocommerce-Price-amount amount\"><bdi><span class=\"woocommerce-Price-currencySymbol\" translate=\"no\">&#36;<\/span>200.00<\/bdi><\/span><\/span>\n<\/a><a href=\"\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct%2F6415&#038;add-to-cart=6032\" aria-describedby=\"woocommerce_loop_add_to_cart_link_describedby_6032\" data-quantity=\"1\" class=\"button product_type_simple add_to_cart_button ajax_add_to_cart\" data-product_id=\"6032\" data-product_sku=\"MiT4100\" aria-label=\"Add to cart: &ldquo;MiT4\u2122&rdquo;\" rel=\"nofollow\" data-success_message=\"&ldquo;MiT4\u2122&rdquo; has been added to your cart\" role=\"button\">Add to cart<\/a>\t<span id=\"woocommerce_loop_add_to_cart_link_describedby_6032\" class=\"screen-reader-text\">\n\t\t\t<\/span>\n<\/li>\n\n\t\t\t\n\t\t\t\t\t<li class=\"desktop-align-left tablet-align-left mobile-align-left product type-product post-45 status-publish instock product_cat-tlr4-agonists has-post-thumbnail taxable shipping-taxable purchasable product-type-simple\">\n\t<a href=\"https:\/\/adjuvants.com\/?product=lit4\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/adjuvants.com\/wp-content\/uploads\/2025\/05\/LiT4-400x400.png\" class=\"attachment-woocommerce_thumbnail size-woocommerce_thumbnail\" alt=\"LiT4Q\u2122\" srcset=\"https:\/\/adjuvants.com\/wp-content\/uploads\/2025\/05\/LiT4-400x400.png 400w, https:\/\/adjuvants.com\/wp-content\/uploads\/2025\/05\/LiT4-300x300.png 300w, https:\/\/adjuvants.com\/wp-content\/uploads\/2025\/05\/LiT4-1024x1024.png 1024w, https:\/\/adjuvants.com\/wp-content\/uploads\/2025\/05\/LiT4-150x150.png 150w, https:\/\/adjuvants.com\/wp-content\/uploads\/2025\/05\/LiT4-768x768.png 768w, https:\/\/adjuvants.com\/wp-content\/uploads\/2025\/05\/LiT4-80x80.png 80w, https:\/\/adjuvants.com\/wp-content\/uploads\/2025\/05\/LiT4-100x100.png 100w, https:\/\/adjuvants.com\/wp-content\/uploads\/2025\/05\/LiT4.png 1254w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><h2 class=\"woocommerce-loop-product__title\">LiT4Q\u2122<\/h2>\n\t<span class=\"price\"><span class=\"woocommerce-Price-amount amount\"><bdi><span class=\"woocommerce-Price-currencySymbol\" translate=\"no\">&#36;<\/span>325.00<\/bdi><\/span><\/span>\n<\/a><a href=\"\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct%2F6415&#038;add-to-cart=45\" aria-describedby=\"woocommerce_loop_add_to_cart_link_describedby_45\" data-quantity=\"1\" class=\"button product_type_simple add_to_cart_button ajax_add_to_cart\" data-product_id=\"45\" data-product_sku=\"LiT4-001\" aria-label=\"Add to cart: &ldquo;LiT4Q\u2122&rdquo;\" rel=\"nofollow\" data-success_message=\"&ldquo;LiT4Q\u2122&rdquo; has been added to your cart\" role=\"button\">Add to cart<\/a>\t<span id=\"woocommerce_loop_add_to_cart_link_describedby_45\" class=\"screen-reader-text\">\n\t\t\t<\/span>\n<\/li>\n\n\t\t\t\n\t\t\t\t\t<li class=\"desktop-align-left tablet-align-left mobile-align-left product type-product post-43 status-publish instock product_cat-tlr4-agonists has-post-thumbnail taxable shipping-taxable purchasable product-type-simple\">\n\t<a href=\"https:\/\/adjuvants.com\/?product=emt4\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><img decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/adjuvants.com\/wp-content\/uploads\/2021\/07\/ADJUVANT_product_badges_300x_EmT4.jpg\" class=\"attachment-woocommerce_thumbnail size-woocommerce_thumbnail\" alt=\"EmT4\u2122\" srcset=\"https:\/\/adjuvants.com\/wp-content\/uploads\/2021\/07\/ADJUVANT_product_badges_300x_EmT4.jpg 300w, https:\/\/adjuvants.com\/wp-content\/uploads\/2021\/07\/ADJUVANT_product_badges_300x_EmT4-200x200.jpg 200w, https:\/\/adjuvants.com\/wp-content\/uploads\/2021\/07\/ADJUVANT_product_badges_300x_EmT4-100x100.jpg 100w, https:\/\/adjuvants.com\/wp-content\/uploads\/2021\/07\/ADJUVANT_product_badges_300x_EmT4-150x150.jpg 150w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><h2 class=\"woocommerce-loop-product__title\">EmT4\u2122<\/h2>\n\t<span class=\"price\"><span class=\"woocommerce-Price-amount amount\"><bdi><span class=\"woocommerce-Price-currencySymbol\" translate=\"no\">&#36;<\/span>250.00<\/bdi><\/span><\/span>\n<\/a><a href=\"\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct%2F6415&#038;add-to-cart=43\" aria-describedby=\"woocommerce_loop_add_to_cart_link_describedby_43\" data-quantity=\"1\" class=\"button product_type_simple add_to_cart_button ajax_add_to_cart\" data-product_id=\"43\" data-product_sku=\"EmT4-001\" aria-label=\"Add to cart: &ldquo;EmT4\u2122&rdquo;\" rel=\"nofollow\" data-success_message=\"&ldquo;EmT4\u2122&rdquo; has been added to your cart\" role=\"button\">Add to cart<\/a>\t<span id=\"woocommerce_loop_add_to_cart_link_describedby_43\" class=\"screen-reader-text\">\n\t\t\t<\/span>\n<\/li>\n\n\t\t\t\n\t\t\t\t\t<li class=\"desktop-align-left tablet-align-left mobile-align-left product type-product post-29 status-publish last instock product_cat-tlr4-agonists has-post-thumbnail taxable shipping-taxable purchasable product-type-simple\">\n\t<a href=\"https:\/\/adjuvants.com\/?product=alt4\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_AIT4_1200x-768x768.jpg\" class=\"attachment-woocommerce_thumbnail size-woocommerce_thumbnail\" alt=\"AlT4\u2122\" srcset=\"https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_AIT4_1200x-768x768.jpg 768w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_AIT4_1200x-300x300.jpg 300w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_AIT4_1200x-1024x1024.jpg 1024w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_AIT4_1200x-150x150.jpg 150w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_AIT4_1200x-200x200.jpg 200w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_AIT4_1200x-100x100.jpg 100w, https:\/\/adjuvants.com\/wp-content\/uploads\/2022\/11\/ADJUVANT_product_badge_AIT4_1200x.jpg 1200w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><h2 class=\"woocommerce-loop-product__title\">AlT4\u2122<\/h2>\n\t<span class=\"price\"><span class=\"woocommerce-Price-amount amount\"><bdi><span class=\"woocommerce-Price-currencySymbol\" translate=\"no\">&#36;<\/span>250.00<\/bdi><\/span><\/span>\n<\/a><a href=\"\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct%2F6415&#038;add-to-cart=29\" aria-describedby=\"woocommerce_loop_add_to_cart_link_describedby_29\" data-quantity=\"1\" class=\"button product_type_simple add_to_cart_button ajax_add_to_cart\" data-product_id=\"29\" data-product_sku=\"AlT4-100\" aria-label=\"Add to cart: &ldquo;AlT4\u2122&rdquo;\" rel=\"nofollow\" data-success_message=\"&ldquo;AlT4\u2122&rdquo; has been added to your cart\" role=\"button\">Add to cart<\/a>\t<span id=\"woocommerce_loop_add_to_cart_link_describedby_29\" class=\"screen-reader-text\">\n\t\t\t<\/span>\n<\/li>\n\n\t\t\t\n\t\t<\/ul>\n\n\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-13b43a1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"13b43a1\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fb1feaa\" data-id=\"fb1feaa\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-38d5d7b elementor-widget elementor-widget-woocommerce-breadcrumb\" data-id=\"38d5d7b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"woocommerce-breadcrumb.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<nav class=\"woocommerce-breadcrumb\" aria-label=\"Breadcrumb\">Home<\/nav>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<h4>LiT4\u2122<br \/>\nTLR4 in a Liposome<\/h4>\n<p>Liposomes consist of vesicles formed by the assembly of phospholipid bilayers. \u00a0These vesicles can be made at ~100 nm diameters and have good stability. \u00a0Liposomes are versatile and biocompatible vehicles for adjuvant formulation. \u00a0As an amphiphilic molecule, the TLR4 agonist will be localized within the lipid bilayer. Furthermore, aqueous adjuvants such as QS21 can be encapsulated in the aqueous interior of the liposomes or solubilized in the aqueous bulk phase forming an adjuvant like the established adjuvant AS01B which has demonstrated good results in malaria, shingles, and TB.<\/p>\n<hr \/>\n<p><strong>Sold in a vial of 0.5 mL.<br \/>\n<\/strong>Research-grade only. Inquire about cGMP.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"featured_media":6435,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[16],"product_tag":[],"class_list":["post-6415","product","type-product","status-publish","has-post-thumbnail","product_cat-tlr4-agonists","desktop-align-left","tablet-align-left","mobile-align-left","first","outofstock","taxable","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>LiT4\u2122 - Adjuvants.com<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/adjuvants.com\/?product=lit4-2\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"LiT4\u2122 - Adjuvants.com\" \/>\n<meta property=\"og:description\" content=\"LiT4\u2122 TLR4 in a Liposome Liposomes consist of vesicles formed by the assembly of phospholipid bilayers. \u00a0These vesicles can be made at ~100 nm diameters and have good stability. \u00a0Liposomes are versatile and biocompatible vehicles for adjuvant formulation. \u00a0As an amphiphilic molecule, the TLR4 agonist will be localized within the lipid bilayer. Furthermore, aqueous adjuvants such as QS21 can be encapsulated in the aqueous interior of the liposomes or solubilized in the aqueous bulk phase forming an adjuvant like the established adjuvant AS01B which has demonstrated good results in malaria, shingles, and TB.    Sold in a vial of 0.5 mL. Research-grade only. 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