AlT4™

AlT4™
TLR4 on Alum

The TLR4 agonist is absorbed onto aluminum hydroxide (alum) particles.  These alum particles consist of nanometer crystals that assemble into aggregates of several micrometers and provide a stable particulate formulation for the sustained release of adjuvant.  In vivo data indicate that TLR4-alum directs the quality of the immune response to a balanced Th1/Th2 response, whereas alum alone induces a strict Th2 response.  The product potential of a TLR4-alum formulation is very promising given that the FDA approved GSK’s cervical cancer vaccine Cervarix® containing a very similar MPL-alum adjuvant formulation.


Sold in a vial of 000 mil.
Research-grade only.

Contact us for a Quote for Bulk Orders

 

$250.00

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