Em™
Oil-in-water squalene emulsion
Sold in a vial of 0.5 mL
Research-grade only. Inquire for cGMP
$195.00
This information is also available on the Downloadable Product Sheet
Initial Details
Adjuvant Name: Em
Chemical Nature: Emulsion
Primary Receptor: Unknown
Secondary Receptor: TLR4
Mechanism of Action: Squalene emulsion possibly triggering inflammasome or through extracellular ATP
Immune Profile Induced:
Drug Master File: No
NIAID Support: Yes
Stability Information: At least 4 years at 2-8 degrees C
Storage Information 2-8 degrees C
In Vivo Use (Preclinical)
Is there an associated publication? No
Disease Area/Pathogen: Virus
Parent Organism: Severe acute respiratory syndrome-related coronavirus
Antigen: Recombinant protein
Immunization Route: IM
Readout: Immunogenicity (serology)
Host Species: Mouse-C57BL/6
Were PK/Toxicology studies conducted? No
Product Grade and Formulation(s)
Product Grade: Research-grade only
Formulation(s): Bedside mixing
Bedside mixing with antigen possible? Yes
Also used in combination adjuvant-formulation? No
Clinical
Not evaluated in humans yet
Em™ is a stabile, squalene-based emulsion used to enhance immune responses to antigens. Generally, the emulsion does not in itself bias the immune response, it will enhance the type of response driven by the antigen alone.
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